Pacing of Left Bundle Branch Area and Atroventricular Node ablatIon in Patients With Symptomatic Atrial Fibrillation
This study aimed to compare the clinical outcomes of left bundle branch area pacing combined with atrioventricular node ablation and pharmacologic treatment optimized according to guidelines in patients with symptomatic atrial fibrillation refractory or intolerant to drug therapy or catheter ablation.
∙ Patients who meet all of the following inclusion criteria 1)-6).
• Permanent atrial fibrillation
• Age ≥ 65 years
• Refractory or intolerant to antiarrhythmic drugs, rate control medications, or catheter ablation
• New York Heart Association (NYHA) functional class II- IV
• LVEF \> 40% (within the past 3 months)
• Patients with at least one of the following:
‣ HF hospitalization (defined as HF as the major reason for hospitalization or treatment for HF lasting ≥12 hours and including treatment with intravenous (IV) diuretics at a healthcare facility) within 12 months
⁃ Elevated NT-proBNP (\>900 pg/ml) in the 30 days prior to enrollment